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Peptide record

TPDB62863

9b2KC Cell-penetrating Peptides modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB62863
9b2KC
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 18-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-KXKKBKKFQILYKBKXKC-NH2

Source notation is retained verbatim; residue identity and the source-provided length have not been independently validated.

Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
18 main sequence record
Amidation Activity
Modified Activity
Linear Activity
Acetylation Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Immortalized Myod-Inducible (Doxycycline) Dm1

Assay & Model

Homozygous transgenic HSALR (line 20 b) mice
Homozygous transgenic HSALR (line 20 b) mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified
Fusogenic
PMO against miR23b and PMO against miR-219
Nucleus
9b2KC-23b peaked at 3-fold change at 200 nM and 9b2KC-218 reached almost a 6-fold increase in MBNL1 at only 10 nM concentration.
Gymnotic delivery
In vitro and in vivo