Back to search

Peptide record

TPDB62856

PF220 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62856
PF220
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Magnetic nanoparticles (MNPs) N-terminal: Stearylation
Sequence
KWLKLWFLKLLKKFL-NH2
Physicochemical Analysis
C106H166N22O16
ARNDCEQGHIMPSTYV
L
2004.62
11.12
5
0
10
+5
-4.37
0.473
156.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
548.73
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
5
K
0
M
2
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
15
C106H166N22O16
2004.62
11.12
+5
-4.37
0.473
Amidation
Magnetic nanoparticles (MNPs)
L
Linear
Stearylation
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U-87 Mg-Luc2, HeLa Pulc 705

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Plasmid (pGL3, splicing correcting oligonucleotides (SCO), and small interfering RNA (siRNA)
In vitro
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC