Peptide record

TPDB62850

Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB62850
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 21-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KWKLFKKYGRKKRRQRRRPPQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C129H218N48O25
ANDCEHIMSTV
RK
2841.46
12.71
12
0
4
+12
5.85
-2.695
18.57
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
2.46
3
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
2
Q
1
G
0
H
0
I
1
L
6
K
0
M
1
F
2
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 1 K: 6 M: 0 F: 1 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
21 main sequence record
C129H218N48O25 sequence-only estimate (linear, free termini)
2841.46 sequence-only estimate (linear, free termini)
12.71 sequence-only estimate (linear, free termini)
+12 sequence-only estimate (linear, free termini)
5.85 sequence-only estimate (linear, free termini)
-2.695 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.