Back to search

Peptide record

TPDB62847

Pep-3 Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62847
Pep-3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, and Peptipedia, with an available 3D structural model.
Chemical: Linker Di-Glycine
Sequence
KWFETWFTEWPKKRKGGC
Physicochemical Analysis
C111H156N28O25S1
ANDQHILMSYV
K
2314.69
10.16
5
2
5
+3
1.51
-1.417
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
712.84
3
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
2
E
0
Q
2
G
0
H
0
I
0
L
4
K
0
M
2
F
1
P
0
S
2
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 2 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 4 M: 0 F: 2 P: 1 S: 0 T: 2 W: 3 Y: 0 V: 0
Chemical Descriptors
18
C111H156N28O25S1
2314.69
10.16
+3
1.51
-1.417
Free
Linker Di-Glycine
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HT-29-luc cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PNA
Endocytosis
In vitro
CCTTTTTSSSCTTSCSCC
Additional Detail Fields 1 fields
CCTTTTTSSSCTTSCSCC