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Peptide record

TPDB62842

XC1 Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB62842
XC1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KVRVRVRYNGTRVRERVK
Physicochemical Analysis
C97H175N39O24
ADCQHILMFPSW
R
2271.70
12.41
8
1
6
+7
8.84
-1.289
80.56
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
65.59
3
Residue Composition
number
0
A
6
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 5
Chemical Descriptors
18
C97H175N39O24
2271.70
12.41
+7
8.84
-1.289
Free
L
Cationic and amphiphilic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic and amphiphilic
Synthetic
NHS-fluorescein and EGFP protein
Cytoplasm
Had greater uptake than XC2
Energy-dependent processes and direct translocation
In vitro