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Peptide record

TPDB62837

XS2 Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB62837
XS2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KVKVKVKVPIGTKVKVKVK
Physicochemical Analysis
C100H189N27O21
ARNDCEQHLMFSWY
K
2105.77
11.36
8
0
8
+8
8.70
0.000
127.37
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
8
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 8 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 7
Chemical Descriptors
19
C100H189N27O21
2105.77
11.36
+8
8.70
0.000
Free
L
Cationic and amphiphilic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic and amphiphilic
Synthetic
NHS-fluorescein and EGFP protein
Cytoplasm
Had lower uptake than both SVS1 and XS1
Energy dependent pathway
In vitro