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Peptide record

TPDB62823

Z13 Cell-penetrating Peptides standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB62823
Z13
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 41-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KRYKNRVASRKSRAKFKQLLHYREVAAAKSSENDRLRLLLK
Physicochemical Analysis
C217H372N74O57
CGIMPTW
RK
4929.80
11.79
15
3
16
+11
13.69
-1.117
83.41
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
60.45
9
Residue Composition
number
5
A
7
R
2
N
1
D
0
C
2
E
1
Q
0
G
1
H
0
I
6
L
7
K
0
M
1
F
0
P
4
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 5 R: 7 N: 2 D: 1 C: 0 E: 2 Q: 1 G: 0 H: 1 I: 0 L: 6 K: 7 M: 0 F: 1 P: 0 S: 4 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
41
C217H372N74O57
4929.80
11.79
+11
13.69
-1.117
Free
L
Linear
Free
N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Dcs(Human And Mouse) , El4 And K562 Cells

Assay & Model

EG7-OVA cells bearing Female C57BL/6J mice
EG7-OVA cells bearing Female C57BL/6J mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
MART1 epitope , OVACD4 epitope and OVACD8 epitope
Z13 was of comparable efficiency on all investigated cell lines.
In vitro and in vivo
CCSSSSSSGGGSCC
Additional Detail Fields 1 fields
CCSSSSSSGGGSCC