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Peptide record

TPDB62822

Z14 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB62822
Z14
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KRYKNRVASRKSRAKFKQLLHYREVAAAK
Physicochemical Analysis
C156H264N54O38
DCGIMPTW
K
3504.15
11.92
12
1
12
+10
9.39
-1.241
64.14
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
85.04
6
Residue Composition
number
5
A
5
R
1
N
0
D
0
C
1
E
1
Q
0
G
1
H
0
I
2
L
6
K
0
M
1
F
0
P
2
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 5 R: 5 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 0 L: 2 K: 6 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
29
C156H264N54O38
3504.15
11.92
+10
9.39
-1.241
Free
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Dcs(Human And Mouse) , El4 And K562 Cells

Assay & Model

EG7-OVA cells bearing Female C57BL/6J mice
EG7-OVA cells bearing Female C57BL/6J mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
MART1 epitope , OVACD4 epitope and OVACD8 epitope
Cell line-dependent transduction efficacy
In vitro and in vivo
CCGGGGGCCTTTTHHHHHHCCTTTSCCCCCCCCCCCCCCC
Additional Detail Fields 1 fields
CCGGGGGCCTTTTHHHHHHCCTTTSCCCCCCCCCCCCCCC