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Peptide record

TPDB62818

Chimera Cell-penetrating Peptides standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB62818
Chimera
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 38-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: α-pheromon N-terminal: Conjugated with TAMRA
Sequence
KRRWRFVWMNPKKKRKVPPWPYLLWWHWLQLKPGQPMY
Physicochemical Analysis
C249H363N67O44S2
ADCEIST
KPW
5063.16
12.03
11
0
17
+10
-2.24
-1.129
56.32
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
35980
710.62
5
Residue Composition
number
0
A
4
R
1
N
0
D
0
C
0
E
2
Q
1
G
1
H
0
I
4
L
6
K
2
M
1
F
6
P
0
S
0
T
6
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 1 I: 0 L: 4 K: 6 M: 2 F: 1 P: 6 S: 0 T: 0 W: 6 Y: 2 V: 2
Chemical Descriptors
38
C249H363N67O44S2
5063.16
12.03
+10
-2.24
-1.129
Free
α-pheromon
L
Linear
Conjugated with TAMRA
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Cerevisiae (Mata And Matα ), Hek293T , Hek293T-Nep And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
TAMRA dye
In vitro
CBTTBCCCCCCGGGTTTTGGGGCCCCCCSSSCCC
Additional Detail Fields 1 fields
CBTTBCCCCCCGGGTTTTGGGGCCCCCCSSSCCC