Peptide record

TPDB62811

Tat (51-57) Cell-penetrating Peptides modified_plain modified
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB62811
Tat (51-57)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
modified_plain
Yes
A 7-aa modified cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer
Sequence
KRRQRRR
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
7 main sequence record
Free Activity
L Activity
Cationic Activity
Linear Activity
Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer Activity
N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Jurkat

Source & Reference

CPPsite3.0
CPPsite3
US 6593292

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (fluorescein)
Probably cytoplasm and nucleus, nucleolus
Low (relative to Tat (49-57))
Probably non-endocytic pathway
In vitro
CCCCCCC
Additional Detail Fields 1 fields
CCCCCCC