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Peptide record

TPDB62808

CPP Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB62808
CPP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Thermosensitive magnetic liposomes (DIR-labelled TSMLs) N-terminal: Dox Attached
Sequence
KRRMKWKK
Physicochemical Analysis
C52H93N19O9S1
ANDCEQGHILFPSTYV
K
1160.49
12.44
6
0
2
+6
3.50
-2.950
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
473.94
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
8
C52H93N19O9S1
1160.49
12.44
+6
3.50
-2.950
Free
Thermosensitive magnetic liposomes (DIR-labelled TSMLs)
L
Linear
Dox Attached
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7

Assay & Model

MCF-7 tumor-bearing female nude mice
MCF-7 tumor-bearing female nude mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Protein derived
DOX
In vitro and in vivo