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Peptide record

TPDB62803

Bipartite nucleoplasmin NLS (155-170) Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB62803
Bipartite nucleoplasmin NLS (155-170)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation
Sequence
KRPAAIKKAGQAKKKK-NH2
Physicochemical Analysis
C78H147N27O18
NDCEHLMFSTWYV
K
1751.20
11.93
8
0
5
+8
7.79
-1.600
49.38
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
0
L
7
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 0 K: 7 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C78H147N27O18
1751.20
11.93
+8
7.79
-1.600
Amidation
L
Cationic
Linear
Biotinylation
N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

EBTr cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060223752

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Biotin
In vitro
CCCHHHHCSCCCCCCC
Additional Detail Fields 1 fields
CCCHHHHCSCCCCCCC