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Peptide record

TPDB62798

GET peptide (P21-8R) Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB62798
GET peptide (P21-8R)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KRKKKGKGLGKKRDPCLRKYKRRRRRRRR
Physicochemical Analysis
C159H299N71O33S1
ANEQHIMFSTWV
R
3765.64
12.65
20
1
3
+19
17.23
-2.831
26.90
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
39.57
2
Residue Composition
number
0
A
11
R
0
N
1
D
1
C
0
E
0
Q
3
G
0
H
0
I
2
L
9
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 11 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 2 K: 9 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
29
C159H299N71O33S1
3765.64
12.65
+19
17.23
-2.831
Free
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bv2 , Nih3T3S (Fibroblasts), U87 (Glioma), And Hmscs

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Chimeric
Magnetic NPs (MNPs) and 5-TAMRA labelled
Perinuclear
At least threefold increase on particle association in the presence of GET
Endocytosis
In vitro