Peptide record

TPDB62729

Crot (27-39) derevative Cell-penetrating Peptides modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62729
Crot (27-39) derevative
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 13-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: X, α-amino-n-butyric acid N-terminal: Conjugation with K-FITC
Sequence
KMDCRPRPKXCKK
Physicochemical Analysis
C61H112N22O15S3
ANEQGHILFSTWYV
K
1489.88
10.55
6
1
1
+5
7.00
-1.877
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
8.39
2
Residue Composition
number
0
A
2
R
0
N
1
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
1
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 1 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C61H112N22O15S3
1489.88
10.55
+5
7.00
-1.877
Free
X, α-amino-n-butyric acid
Modified
Cystein rich
Linear
Conjugation with K-FITC
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

NIH-3T3

Source & Reference

CPPsite3.0
CPPsite3
US20110027300

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Cystein rich
Protein derived
Fluorophore (FITC)
Probably Cytosol
Low (7% of CyLoP1)
Probably Receptor mediated endocytic process
In vitro