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Peptide record

TPDB62727

Crot (27-39) derevative Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62727
Crot (27-39) derevative
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with K-FITC
Sequence
KMDCRPRPKCCKK
Physicochemical Analysis
C64H117N23O16S4
ANEQGHILFSTWYV
K
1593.02
10.17
6
1
1
+5
6.76
-1.685
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
7.85
3
Residue Composition
number
0
A
2
R
0
N
1
D
3
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
1
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 1 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C64H117N23O16S4
1593.02
10.17
+5
6.76
-1.685
Free
L
Cystein rich
Linear
Conjugation with K-FITC
N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

NIH-3T3

Source & Reference

CPPsite3.0
CPPsite3
US20110027300

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cystein rich
Protein derived
Fluorophore (FITC)
Probably Cytosol
Low (9% of CyLoP1)
Probably Receptor mediated endocytic process
In vitro
CCCCCSSCHHHHC
Additional Detail Fields 1 fields
CCCCCSSCHHHHC