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Peptide record

TPDB62726

PN228 (SEQ ID NO: 70) Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB62726
PN228 (SEQ ID NO: 70)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KLWSAWPSLWSSLWKP-NH2
Physicochemical Analysis
C99H138N22O21
RNDCEQGHIMFTYV
SW
1972.32
10.60
2
0
8
+2
-5.85
-0.287
79.38
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
22000
1115.44
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
2
K
0
M
0
F
2
P
4
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 2 M: 0 F: 0 P: 2 S: 4 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
16
C99H138N22O21
1972.32
10.60
+2
-5.85
-0.287
Amidation
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCSCHHHHTTTCCC
Additional Detail Fields 1 fields
CCCCSCHHHHTTTCCC