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Peptide record

TPDB62718

MAP(Aib) Cell-penetrating Peptides modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB62718
MAP(Aib)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 18-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: U, α-amino isobutyric acid (Aib) N-terminal: Acetylation
Sequence
Ac-KLULKLULKULKAULKLU-NH2
Physicochemical Analysis
C75H144N18O14
RNDCEQGHIMFPSTWYV
L
1522.08
11.12
5
0
8
+5
0.86
0.494
157.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
7
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 7 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C75H144N18O14
1522.08
11.12
+5
0.86
0.494
Amidation
U, α-amino isobutyric acid (Aib)
Modified
Amphipathic
Linear
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549 and NIH3T3 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Amphipathic
Synthetic
Nucleic acid [Oligonucleotides (ODNs)]
Cytosol
In vitro