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Peptide record

TPDB62703

Res6 Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB62703
Res6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation
Sequence
KLIKGRTPIKFGKARCRRPPKHSGK-NH2
Physicochemical Analysis
C127H223N45O28S1
NDEQMWYV
K
2860.51
12.43
11
0
5
+10
9.07
-1.288
50.80
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
4
R
0
N
0
D
1
C
0
E
0
Q
3
G
1
H
2
I
1
L
6
K
0
M
1
F
3
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 1 I: 2 L: 1 K: 6 M: 0 F: 1 P: 3 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C127H223N45O28S1
2860.51
12.43
+10
9.07
-1.288
Amidation
L
Cationic
Linear
Biotinylation
N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

EBTr cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060223752

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Biotin
In vitro
CCCSSCSSCCCSCCSSCCCCSSCC
Additional Detail Fields 1 fields
CCCSSCSSCCCSCCSSCCCCSSCC