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Peptide record

TPDB62690

MAP Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB62690
MAP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with fluorescein N-terminal: Acetylation
Sequence
Ac-KLALKLALKALKAALKLAGC
Physicochemical Analysis
C95H177N25O21S1
RNDEQHIMFPSTWYV
L
2037.67
10.71
5
0
13
+5
-0.22
1.000
166.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
6
A
0
R
0
N
0
D
1
C
0
E
0
Q
1
G
0
H
0
I
7
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 7 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C95H177N25O21S1
2037.67
10.71
+5
-0.22
1.000
Conjugation with fluorescein
L
Amphipathic
Linear
Acetylation
N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (fluorescein)
Cytoplasm and nucleus
Lower than MAP (Aib)
In vitro
CCCCTTHHHHHHHHHHHSCC
Additional Detail Fields 1 fields
CCCCTTHHHHHHHHHHHSCC