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Peptide record

TPDB62680

PPC3 Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB62680
PPC3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KKYRGRKRHPR
Physicochemical Analysis
C64H112N28O13
ANDCEQILMFSTWV
R
1481.77
12.42
8
0
1
+7
6.69
-3.291
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
100.56
1
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
3
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C64H112N28O13
1481.77
12.42
+7
6.69
-3.291
Free
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PMO and Cy5.5 dye
Increased fluorescence by 4.4-fold
Macropinocytosis
In vitro
CCSCCTTSSSCC
Additional Detail Fields 1 fields
CCSCCTTSSSCC