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Peptide record

TPDB62648

ch-K3R8 Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB62648
ch-K3R8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Micelles N-terminal: Conjugated with CHOlesterol
Sequence
KKKRRRRRRRR
Physicochemical Analysis
C66H134N38O12
ANDCEQGHILMFPSTWYV
R
1652.04
13.25
11
0
0
+11
9.45
-4.336
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C66H134N38O12
1652.04
13.25
+11
9.45
-4.336
Free
Micelles
L
Cationic
Linear
Conjugated with CHOlesterol
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 Cells, Bcecs And U251 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
YOYO-1 labelled pEGFP
Nucleus
Lowest EGFP fluorescence intensity than others
In vitro
CCCGGGSCCCC
Additional Detail Fields 1 fields
CCCGGGSCCCC