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Peptide record

TPDB62646

1746c27_SpyT Cell-penetrating Peptides standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB62646
1746c27_SpyT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 44-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KKKKQPPKPKKPKTQEKKKKQPPKPKRGASAHIVMVDAYKPTKG
Physicochemical Analysis
C226H392N68O56S1
NCLFW
K
4990.08
11.15
18
2
8
+15
24.78
-1.920
28.86
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
29.86
7
Residue Composition
number
3
A
1
R
0
N
1
D
0
C
1
E
3
Q
2
G
1
H
1
I
0
L
16
K
1
M
0
F
8
P
1
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 1 C: 0 E: 1 Q: 3 G: 2 H: 1 I: 1 L: 0 K: 16 M: 1 F: 0 P: 8 S: 1 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
44
C226H392N68O56S1
4990.08
11.15
+15
24.78
-1.920
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Or T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
β-lactamase protein and CCF2-AM cell-permeable dye
Cytoplasm
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC