Back to search

Peptide record

TPDB62634

P12 Cell-penetrating Peptides modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62634
P12
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 14-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Modified, details unspecified
Sequence
KKKKKQBKKKHRWP
Physicochemical Analysis
C81H142N28O15
ANDCEGILMFSTYV
K
1748.20
11.97
10
0
1
+9
8.87
-3.207
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
314.61
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
0
L
8
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 0 K: 8 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C81H142N28O15
1748.20
11.97
+9
8.87
-3.207
Free
Modified
Cationic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654 Cells

Source & Reference

CPPsite3.0
CPPsite3
WO2020028254A1, WO2019178479A1, WO2019079386A1,WO2019079367A0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Cationic
Synthetic
PMO anti-IVS2-666
Cytosol and Nucleus
Receptor mediated endocytosis
In vitro