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Peptide record

TPDB62631

P1 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB62631
P1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Linker 6-aminohexamoic acid (Ahx) N-terminal: Conjugation with FITC
Sequence
KKKKKKNKKLQQRGD
Physicochemical Analysis
C80H151N29O21
ACEHIMFPSTWYV
K
1855.26
11.32
9
1
1
+8
10.99
-3.087
26.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
1
R
1
N
1
D
0
C
0
E
2
Q
1
G
0
H
0
I
1
L
8
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 1 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 1 K: 8 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C80H151N29O21
1855.26
11.32
+8
10.99
-3.087
Free
Linker 6-aminohexamoic acid (Ahx)
L
Cationic
Linear
Conjugation with FITC
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (FITC)
Punctate cytoplasmic
Medium (compare to Tat)
In vitro
CCSTTTCCTTTTSCC
Additional Detail Fields 1 fields
CCSTTTCCTTTTSCC