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Peptide record

TPDB62617

CL22 Cell-penetrating Peptides standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB62617
CL22
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 34-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
KKKKKKGGFLGFWRGENGRKTRSAYERMCILKGK
Physicochemical Analysis
C178H297N57O43S2
DQHPV
K
3987.79
11.31
13
2
9
+11
9.82
-1.347
37.35
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
175.28
5
Residue Composition
number
1
A
4
R
1
N
0
D
1
C
2
E
0
Q
6
G
0
H
1
I
2
L
9
K
1
M
2
F
0
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 0 C: 1 E: 2 Q: 0 G: 6 H: 0 I: 1 L: 2 K: 9 M: 1 F: 2 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
34
C178H297N57O43S2
3987.79
11.31
+11
9.82
-1.347
L
Linear
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human monocyte-derived DCs

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid
In vitro
CCTTSSSSCCSCCSGGGTCCCSCHHHHSCSCCCC
Additional Detail Fields 1 fields
CCTTSSSSCCSCCSGGGTCCCSCHHHHSCSCCCC