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Peptide record

TPDB62608

PN361 (SEQ ID NO: 58) Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB62608
PN361 (SEQ ID NO: 58)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKDGKKRKRSRKESYSVYVYKVLKQ-NH2
Physicochemical Analysis
C139H237N43O37
ANCHIMFPTW
K
3102.68
10.83
11
2
7
+9
11.41
-1.820
50.40
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
4470
144.07
7
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
1
E
1
Q
1
G
0
H
0
I
1
L
8
K
0
M
0
F
0
P
3
S
0
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 8 M: 0 F: 0 P: 0 S: 3 T: 0 W: 0 Y: 3 V: 3
Chemical Descriptors
25
C139H237N43O37
3102.68
10.83
+9
11.41
-1.820
Amidation
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCGGGSCCCSSCCCSSCSCTTTCC
Additional Detail Fields 1 fields
CCCGGGSCCCSSCCCSSCSCTTTCC