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Peptide record

TPDB62594

KH Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB62594
KH
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KHKHKHKHKK
Physicochemical Analysis
C60H102N24O11
ARNDCEQGILMFPSTWYV
K
1335.62
11.21
10
0
0
+6
9.78
-3.620
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
4
H
0
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 4 I: 0 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C60H102N24O11
1335.62
11.21
+6
9.78
-3.620
Free
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
HF488 labelled PNAs with 2-aminopyridine (M)
Cytosol
Uptake of PNA-KH was similar to that of Tat and octa-arginine conjugates
In vitro