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Peptide record

TPDB62585

SVM3 Blood-Brain Barrier Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB62585
SVM3
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CPPsite3.0
standard
No
A 16-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict and CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with Cyanine5.5 (Cy5.5)
Sequence
KGTYKKKLMRIPLKGT
Physicochemical Analysis
C85H152N24O20S1
ANDCEQHFSWV
K
1862.35
11.14
6
0
5
+6
3.91
-0.944
73.12
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
80.01
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
2
L
5
K
1
M
0
F
1
P
0
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 5 M: 1 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
16
C85H152N24O20S1
1862.35
11.14
+6
3.91
-0.944
Free
L
Amphipathic
Linear
Conjugated with Cyanine5.5 (Cy5.5)
N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Primary Human Astrocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Cy5.5 dye
In vitro
CCCCCTTSSSCCCCSSSCC
Additional Detail Fields 1 fields
CCCCCTTSSSCCCCSSSCC