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Peptide record

TPDB62582

Res4 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB62582
Res4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation
Sequence
KGRTPIKFGKADCDRPPKHSQNGMGK-NH2
Physicochemical Analysis
C121H201N41O35S2
ELWYV
K
2854.30
10.70
8
2
4
+5
10.57
-1.542
18.85
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
1
A
2
R
1
N
2
D
1
C
0
E
1
Q
4
G
1
H
1
I
0
L
5
K
1
M
1
F
3
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 2 C: 1 E: 0 Q: 1 G: 4 H: 1 I: 1 L: 0 K: 5 M: 1 F: 1 P: 3 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C121H201N41O35S2
2854.30
10.70
+5
10.57
-1.542
Amidation
L
Cationic
Linear
Biotinylation
N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

EBTr cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060223752

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Biotin
In vitro
CCCCCBSSSSSCCCCSSSCSCSBCC
Additional Detail Fields 1 fields
CCCCCBSSSSSCCCCSSSCSCSBCC