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Peptide record

TPDB62573

ParasinK Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB62573
ParasinK
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KGKGKQGGKVKAKWKTKSS
Physicochemical Analysis
C90H159N29O24
RNDCEHILMFPY
K
2031.43
11.36
8
0
3
+8
6.99
-1.763
20.53
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
270.74
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
4
G
0
H
0
I
0
L
8
K
0
M
0
F
0
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 0 I: 0 L: 0 K: 8 M: 0 F: 0 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
19
C90H159N29O24
2031.43
11.36
+8
6.99
-1.763
Free
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Strain Carolina #25922

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Higher arginine content increased permeabilization for parasin
In vitro
CCCCCSSSSCCTTTSSSCCC
Additional Detail Fields 1 fields
CCCCCSSSSCCTTTSSSCCC