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Peptide record

TPDB62564

PN183 (SEQ ID NO: 63) Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB62564
PN183 (SEQ ID NO: 63)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 28-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KETWWETWWTEWSQPGRKKRRQRRRPPQ-NH2
Physicochemical Analysis
C171H255N57O42
ANDCHILMFYV
R
3781.26
12.12
9
3
5
+6
8.29
-2.582
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
27500
727.27
7
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
3
E
3
Q
1
G
0
H
0
I
0
L
3
K
0
M
0
F
3
P
1
S
3
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 3 Q: 3 G: 1 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 3 S: 1 T: 3 W: 5 Y: 0 V: 0
Chemical Descriptors
28
C171H255N57O42
3781.26
12.12
+6
8.29
-2.582
Amidation
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCTTTTTTSSCCSGGGGCTTCCCCCC
Additional Detail Fields 1 fields
CCCCTTTTTTSSCCSGGGGCTTCCCCCC