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Peptide record

TPDB62562

PEP-1 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62562
PEP-1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KETWWETWWTEW
Physicochemical Analysis
C88H106N18O22
ARNDCQGHILMFPSYV
W
1767.92
3.96
1
3
5
-2
-1.78
-1.750
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
27500
1555.50
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
3
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
3
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 3 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 3 W: 5 Y: 0 V: 0
Chemical Descriptors
12
C88H106N18O22
1767.92
3.96
-2
-1.78
-1.750
Free
L
Cationic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ccl-20.2 Freshly Enucleated Pig Eyes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Protein derived
5-carboxyfluorescein (5-FAM)
Nucleus
8 fold lower permeability coefficient than PNT
In vitro and ex vivo