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Peptide record

TPDB62535

Dot1l Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB62535
Dot1l
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: FITC-(Acp)--labelled
Sequence
KARKKKLNKKGRKMAGRKRGRPKK
Physicochemical Analysis
C122H234N50O26S1
DCEQHIFSTWYV
K
2849.58
13.02
15
0
4
+15
13.72
-2.437
24.58
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
5
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
1
L
10
K
1
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 5 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 10 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C122H234N50O26S1
2849.58
13.02
+15
13.72
-2.437
Free
FITC-(Acp)--labelled
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCSC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C1OO1
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF7, A549 , HeLa , HEPG2, RAW264.7 And Rat T6 Cells Primary Cultured Cells, Liver Cells And Hepatic Parenchymal Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
HaloTag
In vitro
CCCCSSCCCCCCCCCCSSSCCSCC
Additional Detail Fields 1 fields
CCCCSSCCCCCCCCCCSSSCCSCC