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Peptide record

TPDB62533

Vaspin31−50 (VaspinHA1) Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB62533
Vaspin31−50 (VaspinHA1)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with TAMRA
Sequence
KALSEVQGWKQRMAAKELAR
Physicochemical Analysis
C100H170N32O28S1
NDCHIFPTY
A
2300.71
10.81
5
2
9
+3
6.12
-0.795
73.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
239.06
3
Residue Composition
number
4
A
2
R
0
N
0
D
0
C
2
E
2
Q
1
G
0
H
0
I
2
L
3
K
1
M
0
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 2 G: 1 H: 0 I: 0 L: 2 K: 3 M: 1 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
20
C100H170N32O28S1
2300.71
10.81
+3
6.12
-0.795
Free
L
Linear
Conjugated with TAMRA
N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

3T3-L1, Scat, Epiat, Imba, Hepg2 And Hek293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
TAMRA dye
3T3-L1 cells to be >10-fold higher than in HEK293 cells
In vitro
CTTHHHHHHCCSSCTTSSCC
Additional Detail Fields 1 fields
CTTHHHHHHCCSSCTTSSCC