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Peptide record

TPDB62520

TCTP (3-10) deletion mutant Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB62520
TCTP (3-10) deletion mutant
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with rhodamine B
Sequence
IYRDLISH-NH2
Physicochemical Analysis
C46H73N13O13
ANCEQGKMFPTWV
I
1016.16
7.77
2
1
4
+0
1.01
-0.062
146.25
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
146.63
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
2
I
1
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
8
C46H73N13O13
1016.16
7.77
+0
1.01
-0.062
Amidation
L
Linear
Conjugation with rhodamine B
N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=NC=NC1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3
US 20100168034

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (Rhodamine)
Cytoplasm and nucleus
In vitro
CCTTTCC
Additional Detail Fields 1 fields
CCTTTCC