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Peptide record

TPDB62517

AHB-2 Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB62517
AHB-2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
IYKTPPIKDFGGFNFSQIL
Physicochemical Analysis
C106H157N23O27
ARCEHMWV
IF
2185.55
9.65
2
1
8
+1
-0.42
0.032
82.11
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
68.18
5
Residue Composition
number
0
A
0
R
1
N
1
D
0
C
0
E
1
Q
2
G
0
H
3
I
1
L
2
K
0
M
3
F
2
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 3 L: 1 K: 2 M: 0 F: 3 P: 2 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
19
C106H157N23O27
2185.55
9.65
+1
-0.42
0.032
Free
L
Cationic and amphipathic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Vero Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic and amphipathic
Synthetic
Chitosan nanoparticles
Cytosol
44.52 ± 2.33% internalization
Endocytosis
In vitro
CCSSGGGSCCC
Additional Detail Fields 1 fields
CCSSGGGSCCC