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Peptide record

TPDB62494

I31KP (AF +Antp) Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB62494
I31KP (AF +Antp)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: GGGG as a Linker
Sequence
ITDFGIFIGLGGGGSRQIKIWFQNRRMKWKK
Physicochemical Analysis
C169H265N49O39S1
ACEHPYV
G
3639.33
12.16
7
1
12
+6
0.10
-0.394
75.48
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
11000
302.25
5
Residue Composition
number
0
A
3
R
1
N
1
D
0
C
0
E
2
Q
6
G
0
H
5
I
1
L
4
K
1
M
3
F
0
P
1
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 0 E: 0 Q: 2 G: 6 H: 0 I: 5 L: 1 K: 4 M: 1 F: 3 P: 0 S: 1 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
31
C169H265N49O39S1
3639.33
12.16
+6
0.10
-0.394
Free
GGGG as a Linker
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]1CC(=O)OOC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC1=O)Cc1ccccc1)[C@@H](C)CC)Cc1ccccc1)[C@@H](C)CC)CC(C)C
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bt474 Cells S. Aureus, Mrsa, And B. Cereus

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Amyloidogenic fragment (AF) at N terminal
In vitro
CCCHHHHHSCCSSCCSSSCSSCC
Additional Detail Fields 1 fields
CCCHHHHHSCCSSCCSSSCSSCC