Peptide record

TPDB62484

IRF5-CPP1 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB62484
IRF5-CPP1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-IRLQISNPYLKFIPLKRAIWLIK-NH2
Physicochemical Analysis
C138H227N35O28
DCEGHMTV
I
2824.54
11.59
5
0
13
+5
-1.26
0.365
156.96
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
6990
247.47
4
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
5
I
4
L
3
K
0
M
1
F
2
P
1
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 5 L: 4 K: 3 M: 0 F: 1 P: 2 S: 1 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
23
C138H227N35O28
2824.54
11.59
+5
-1.26
0.365
Amidation
L
Linear
Acetylation
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PBMCs, Cd19+ B Cells, Cd14+ Monocytes, And Bdca2+Cd123+ Plasmacytoid Dendritic Cells (Pdcs), HeLa And THP-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
FITC dye
In vitro
CCCCCCTTCC
Additional Detail Fields 1 fields
CCCCCCTTCC