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Peptide record

TPDB62482

No.143 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB62482
No.143
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
IPSRWKDQFWKRWHY
Physicochemical Analysis
C104H141N29O21
ANCEGLMTV
W
2133.45
10.71
5
1
6
+3
-0.98
-1.740
26.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
17990
843.24
3
Residue Composition
number
0
A
2
R
0
N
1
D
0
C
0
E
1
Q
0
G
1
H
1
I
0
L
2
K
0
M
1
F
1
P
1
S
0
T
3
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 0 K: 2 M: 0 F: 1 P: 1 S: 1 T: 0 W: 3 Y: 1 V: 0
Chemical Descriptors
15
C104H141N29O21
2133.45
10.71
+3
-0.98
-1.740
Free
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, Jurkat and CHO

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (fluorescein)
Similar or greater than TAT in CHO cells, greater
In vitro
CCSTHHHHHHHTCC
Additional Detail Fields 1 fields
CCSTHHHHHHHTCC