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Peptide record

TPDB62467

IRF5-CPP8 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB62467
IRF5-CPP8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-IKVMWPILFIIKLVHSDKKI-NH2
Physicochemical Analysis
C119H197N27O24S1
ARNCEQGTY
I
2422.10
10.55
5
1
12
+3
0.99
0.880
165.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
227.08
1
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
5
I
2
L
4
K
1
M
1
F
1
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 5 L: 2 K: 4 M: 1 F: 1 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
20
C119H197N27O24S1
2422.10
10.55
+3
0.99
0.880
Amidation
L
Linear
Acetylation
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PBMCs, Cd19+ B Cells, Cd14+ Monocytes, And Bdca2+Cd123+ Plasmacytoid Dendritic Cells (Pdcs), HeLa And THP-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
FITC dye
In vitro
CCCTTHHHHHHHHHHHHTTSSSCCCCCC
Additional Detail Fields 1 fields
CCCTTHHHHHHHHHHHHTTSSSCCCCCC