Back to search

Peptide record

TPDB62457

IL15 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62457
IL15
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
IIHNEKVQAHGKKVL
Physicochemical Analysis
C77H132N24O20
RDCMFPSTWY
K
1714.04
10.32
5
1
6
+2
6.71
-0.400
123.33
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
1
E
1
Q
1
G
2
H
2
I
1
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 2 I: 2 L: 1 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
15
C77H132N24O20
1714.04
10.32
+2
6.71
-0.400
Free
L
Hydrophobic
Linear
Free
N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PBMC, Vero Cells, Hacat Cells, And 3T3-L1 Cells

Assay & Model

Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATCC 27736), Pseudomonas aeruginosa (ATCC 27853), Bacillus subtilis (ATCC 6633), Staphylococcus aureus (ATCC 25923) and Staphylococcus epidermidis
Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATCC 27736), Pseudomonas aeruginosa (ATCC 27853), Bacillus subtilis (ATCC 6633), Staphylococcus aureus (ATCC 25923) and Staphylococcus epidermidis

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Synthetic
Lower membrane depth penetrating IL15 had very high MIC(>200 μg/mL for all strains).
In vitro and in vivo
CCSSSHHHHSCCCCC
Additional Detail Fields 1 fields
CCSSSHHHHSCCCCC