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Peptide record

TPDB62453

YTA4 Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB62453
YTA4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
IAWVKAFIRKLRKGPLG-NH2
Physicochemical Analysis
C94H157N27O18
NDCEQHMSTY
K
1953.45
12.43
5
0
9
+5
0.07
0.188
120.59
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
281.55
0
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
2
L
3
K
0
M
1
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 3 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
17
C94H157N27O18
1953.45
12.43
+5
0.07
0.188
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MDA-MB-231

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (fluorescein)
In vitro
CHHHHTHHHHTTTSSCC
Additional Detail Fields 1 fields
CHHHHTHHHHTTTSSCC