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Peptide record

TPDB62448

LB1_10 Cell-penetrating Peptides modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB62448
LB1_10
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 17-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: X, aminohexyl residue N-terminal: N-terminal alkyne is introduced using 4-pentynoic acid
Sequence
HXRHXRILFQYHXRHXR-NH2
Physicochemical Analysis
C83H126N34O16
ANDCEGKMPSTWV
RH
1856.13
12.40
8
0
4
+4
4.72
-1.441
45.88
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
1490
80.27
2
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
1
Q
0
G
4
H
1
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 4 I: 1 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
17
C83H126N34O16
1856.13
12.40
+4
4.72
-1.441
Amidation
X, aminohexyl residue
Modified
Cationic
Linear
N-terminal alkyne is introduced using 4-pentynoic acid
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa pLuc705 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Cationic
Synthetic
PNA705
In vitro