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Peptide record

TPDB62444

HSN Cell-penetrating Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB62444
HSN
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 7-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
HSNDPRN
Physicochemical Analysis
C32H50N14O13
ACEQGILKMFTWYV
N
838.83
7.85
2
1
0
+0
4.42
-2.943
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
2
N
1
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C32H50N14O13
838.83
7.85
+0
4.42
-2.943
Free
L
Cyclic
Free
N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Caco-2 Cells

Assay & Model

Male ICR mice (mouse intestinal epithelium)
Male ICR mice (mouse intestinal epithelium)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L
Phage Display
M13 phage
The amounts of HSN-phage was 23.8-fold greater than that of control phage at 30 min
In vitro and in vivo
CCCTTC
Additional Detail Fields 1 fields
CCCTTC