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Peptide record

TPDB62437

Peptide 12 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62437
Peptide 12
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
HRHIRRQSLIML
Physicochemical Analysis
C67H118N26O15S1
ANDCEGKFPTWYV
R
1559.90
12.70
5
0
5
+3
3.09
-0.475
130.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
1
Q
0
G
2
H
2
I
2
L
0
K
1
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 2 I: 2 L: 2 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C67H118N26O15S1
1559.90
12.70
+3
3.09
-0.475
L
Linear
N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HIG-82 cells

Source & Reference

CPPsite3.0
CPPsite3
US 6881825

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Phages
In vitro
CCSSSCSCCC
Additional Detail Fields 1 fields
CCSSSCSCCC