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Peptide record

TPDB62432

Peptide 54 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62432
Peptide 54
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
HPGSPFPPEHRP
Physicochemical Analysis
C62H87N19O16
ANDCQILKMTWYV
P
1354.49
8.00
3
1
1
+0
6.01
-1.733
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
1
E
0
Q
1
G
2
H
0
I
0
L
0
K
0
M
1
F
5
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 2 I: 0 L: 0 K: 0 M: 0 F: 1 P: 5 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C62H87N19O16
1354.49
8.00
+0
6.01
-1.733
L
Linear
N[C@@H](Cc1[nH]cnc1)C(=O)N1CCC[C@H]1C(=O)/N=C/C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Calu 3 cells

Source & Reference

CPPsite3.0
CPPsite3
US 6881825

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Phages
In vitro
CCSSSSSSCC
Additional Detail Fields 1 fields
CCSSSSSSCC