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Peptide record

TPDB62428

PF141 Cell-penetrating Peptides modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
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TPDB62428
PF141
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 21-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Stearylation
Sequence
HLHHLLKLLOOLAAAALOOLL-NH2
Physicochemical Analysis
C90H154N24O18
RNDCEQGIMFPSTWYV
L
1860.36
10.10
4
0
13
+1
-1.85
1.329
186.19
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
3
H
0
I
9
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 3 I: 0 L: 9 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C90H154N24O18
1860.36
10.10
+1
-1.85
1.329
Amidation
Modified
Amphipathic
Linear
Stearylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Pluc 705 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Amphipathic
Synthetic
Splice correcting oligonucleotide (PS-20-OMe SCO)
Fold increase in activity over treatment with oligonucleotide alone.
In vitro