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Peptide record

TPDB62424

Peptide 30 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62424
Peptide 30
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
HIQLSPFSQSWR
Physicochemical Analysis
C68H100N20O18
ANDCEGKMTYV
S
1485.67
11.05
2
0
4
+1
-0.08
-0.708
65.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
5500
370.20
5
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
2
Q
0
G
1
H
1
I
1
L
0
K
0
M
1
F
1
P
3
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 1 P: 1 S: 3 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C68H100N20O18
1485.67
11.05
+1
-0.08
-0.708
L
Linear
N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HIG-82 cells

Source & Reference

CPPsite3.0
CPPsite3
US 6881825

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Phages
In vitro
CCCCCSSSCCC
Additional Detail Fields 1 fields
CCCCCSSSCCC