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Peptide record

TPDB62377

Peptide 29 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62377
Peptide 29
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
HFAAWGGWSLVH
Physicochemical Analysis
C67H86N18O14
RNDCEQIKMPTY
AGHW
1367.53
8.00
2
0
7
+0
-3.59
0.383
73.33
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
11000
804.37
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
2
H
0
I
1
L
0
K
0
M
1
F
0
P
1
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 2 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
12
C67H86N18O14
1367.53
8.00
+0
-3.59
0.383
L
Linear
N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HIG-82 cells

Source & Reference

CPPsite3.0
CPPsite3
US 6881825

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Phages
In vitro
CCSSCCCCCC
Additional Detail Fields 1 fields
CCSSCCCCCC