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Peptide record

TPDB62368

GST-(HE)8EFG5YG(RG)6 Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB62368
GST-(HE)8EFG5YG(RG)6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
N-terminal: Conjugated with GST
Sequence
HEHEHEHEHEHEHEHEEFGGGGGYGRGRGRGRGRGRG
Physicochemical Analysis
C171H247N71O57
ANDCQILKMPSTWV
G
4209.28
6.24
14
9
2
-2
28.77
-2.362
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
1490
35.40
1
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
9
E
0
Q
12
G
8
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 9 Q: 0 G: 12 H: 8 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
37
C171H247N71O57
4209.28
6.24
-2
28.77
-2.362
Free
L
Cationic
Linear
Conjugated with GST
N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Protein (GST)
Higher uptake efficiency
In vitro
CCSSCSSSSCTTTSCSCCCSCSSSCCSCC
Additional Detail Fields 1 fields
CCSSCSSSSCTTTSCSCCCSCSSSCCSCC